Dichloromethane → 3-{1-[4-(3-Methyl-4-trifluoromethyl-phenyl)-6-trifluoromethyl-pyrimidin-2-yl]-1H-imidazol-4-yl}-benzenesulfonamide

HRID 1551292Notes

Reaction equation

HRID 1551292 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[NH:5][S:6](=[O:7])(=[O:8])[c:9]1[cH:10][c:11](-[c:15]2[n:16][cH:17][n:18](-[c:20]3[n:21][c:22](-[c:30]4[cH:31][c:32]([CH3:40])[c:33]([C:36]([F:37])([F:38])[F:39])[cH:34][cH:35]4)[cH:23][c:24]([C:26]([F:27])([F:28])[F:29])[n:25]3)[cH:19]2)[cH:12][cH:13][cH:14]1.[Cl:48][CH2:49][Cl:50].[F:41][C:42]([F:43])([F:44])[C:45]([OH:46])=[O:47]>>[NH2:5][S:6](=[O:7])(=[O:8])[c:9]1[cH:10][c:11](-[c:15]2[n:16][cH:17][n:18](-[c:20]3[n:21][c:22](-[c:30]4[cH:31][c:32]([CH3:40])[c:33]([C:36]([F:37])([F:38])[F:39])[cH:34][cH:35]4)[cH:23][c:24]([C:26]([F:27])([F:28])[F:29])[n:25]3)[cH:19]2)[cH:12][cH:13][cH:14]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 57468983N-tert-butyl-3-{1-[6-(3-methyl-4-trifluoromethylphenyl)-4-trifluoromethyl-pyrimidin-2-yl]-1H-imidazol-4-yl}-benzenesulfonamide

Product 1

HCID 574689823-{1-[4-(3-Methyl-4-trifluoromethyl-phenyl)-6-trifluoromethyl-pyrimidin-2-yl]-1H-imidazol-4-yl}-benzenesulfonamide

Sources & evidence

ORD record
ord-d77f09bf90704f12b59e44fae02af8e7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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