Chloroform → N-[3-hydroxy-1-[2-(pyrimidin-2-ylamino)ethyl]piperidin-4-yl]-3-(trifluoromethyl)benzamide
Reaction equation
[CH3:35][CH2:36][N:37]([CH2:38][CH3:39])[CH2:40][CH3:41].[Cl:18][CH:19]([Cl:20])[Cl:21].[F:22][C:23]([c:24]1[cH:25][c:26]([C:27](=[O:28])[Cl:29])[cH:30][cH:31][cH:32]1)([F:33])[F:34].[NH2:1][CH:2]1[CH:3]([OH:17])[CH2:4][N:5]([CH2:8][CH2:9][NH:10][c:11]2[n:12][cH:13][cH:14][cH:15][n:16]2)[CH2:6][CH2:7]1>>[NH:1]([CH:2]1[CH:3]([OH:17])[CH2:4][N:5]([CH2:8][CH2:9][NH:10][c:11]2[n:12][cH:13][cH:14][cH:15][n:16]2)[CH2:6][CH2:7]1)[C:27]([c:26]1[cH:25][c:24]([C:23]([F:22])([F:33])[F:34])[cH:32][cH:31][cH:30]1)=[O:28]Participants
5
Sources & evidence
- ORD record
- ord-84ed8e03393948bf9188aa63173fcdc6
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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