Acetic Acid → 1-[2-(4-Amino-piperidin-1-yl)-ethyl]-3-(2-methyl-quinolin-4-yl)-urea

HRID 1551471Notes

Reaction equation

HRID 1551471 reaction equation
[C:1]([O:2][C:3](=[O:4])[NH:7][CH:8]1[CH2:9][CH2:10][N:11]([CH2:14][CH2:15][NH:16][C:17](=[O:18])[NH:19][c:20]2[cH:21][c:22]([CH3:30])[n:23][c:24]3[cH:25][cH:26][cH:27][cH:28][c:29]23)[CH2:12][CH2:13]1)([CH3:5])([CH3:6])[CH3:31].[C:33]([OH:34])(=[O:35])[CH3:36].[ClH:32]>>[NH2:7][CH:8]1[CH2:9][CH2:10][N:11]([CH2:14][CH2:15][NH:16][C:17](=[O:18])[NH:19][c:20]2[cH:21][c:22]([CH3:30])[n:23][c:24]3[cH:25][cH:26][cH:27][cH:28][c:29]23)[CH2:12][CH2:13]1

Participants

4

Reactant 3

HCID 176Acetic AcidHCID 313Hydrochloric AcidHCID 59715916(1-{2-[3-(2-Methyl-quinolin-4-yl)-ureido]-ethyl}-piperidin-4-yl)-carbamic acid tert-butyl ester

Product 1

HCID 597159051-[2-(4-Amino-piperidin-1-yl)-ethyl]-3-(2-methyl-quinolin-4-yl)-urea

Sources & evidence

ORD record
ord-2b17e23c19e04592bd5064ed4a0a7246
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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