4-Chloroaniline → 5-(3-(9-(4-methoxybenzyl)-9H-purin-6-yl)pyridin-2-yloxy)-N-(4-chlorophenyl)-6-methylisoquinolin-1-amine
Reaction equation
[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]([CH2:7][n:8]2[c:9]3[n:10][cH:11][n:12][c:13](-[c:17]4[c:18]([O:23][c:24]5[c:25]6[cH:26][cH:27][n:28][c:29]([Cl:35])[c:30]6[cH:31][cH:32][c:33]5[CH3:34])[n:19][cH:20][cH:21][cH:22]4)[c:14]3[n:15][cH:16]2)[cH:36][cH:37]1.[CH3:74][Si:75]([N-:76][Si:77]([CH3:78])([CH3:79])[CH3:80])([CH3:81])[CH3:82].[CH:46]1([P:47]([CH:48]2[CH2:49][CH2:50][CH2:51][CH2:52][CH2:53]2)[c:54]2[cH:55][cH:56][cH:57][cH:58][c:59]2-[c:60]2[cH:61][cH:62][cH:63][cH:64][c:65]2[N:66]([CH3:67])[CH3:68])[CH2:69][CH2:70][CH2:71][CH2:72][CH2:73]1.[Li+:83].[NH2:38][c:39]1[cH:40][cH:41][c:42]([Cl:43])[cH:44][cH:45]1.[O:84]1[CH2:85][CH2:86][O:87][CH2:88][CH2:89]1>>[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]([CH2:7][n:8]2[c:9]3[n:10][cH:11][n:12][c:13](-[c:17]4[c:18]([O:23][c:24]5[c:25]6[cH:26][cH:27][n:28][c:29]([NH:38][c:39]7[cH:40][cH:41][c:42]([Cl:43])[cH:44][cH:45]7)[c:30]6[cH:31][cH:32][c:33]5[CH3:34])[n:19][cH:20][cH:21][cH:22]4)[c:14]3[n:15][cH:16]2)[cH:36][cH:37]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-92ed8843d2434d70acc06fcdaaed9e8b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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