Bicarbonate Ion → 2-[5-Ethynyl-1-(2-trimethylsilanyl-ethoxymethyl)-1H-imidazol-2-yl]-pyrrolidine-1-carboxylic acid tert-butyl ester

HRID 1551502Notes

Reaction equation

HRID 1551502 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]([c:13]2[n:14]([CH2:20][O:21][CH2:22][CH2:23][Si:24]([CH3:25])([CH3:26])[CH3:27])[c:15]([CH:18]=[O:19])[cH:16][n:17]2)[CH2:10][CH2:11][CH2:12]1.[C:40](=[O:41])([O-:42])[O-:43].[C:46](=[O:47])([OH:48])[O-:49].[CH2:53]1[O:54][CH2:55][CH2:56][CH2:57]1.[CH3:28][CH:29]([CH3:30])[C:31](=[O:32])[C:33]([P:34](=[O:35])([O-:36])[O-:37])=[N+:38]=[N-:39].[CH3:51][OH:52].[K+:44].[K+:45].[Na+:50]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]([c:13]2[n:14]([CH2:20][O:21][CH2:22][CH2:23][Si:24]([CH3:25])([CH3:26])[CH3:27])[c:15]([C:18]#[CH:28])[cH:16][n:17]2)[CH2:10][CH2:11][CH2:12]1

Participants

9

Reactant 8

HCID 769Bicarbonate IonHCID 813Potassium Cation2×HCID 887MethanolHCID 923Sodium ionHCID 8028TetrahydrofuranHCID 19660Carbonate IonHCID 723380662-[5-Formyl-1-(2-trimethylsilanyl-ethoxymethyl)-1H-imidazol-2-yl]-pyrrolidine-1-carboxylic acid tert-butyl esterHCID 86586111Dimethyl-1-diazo-2-oxopropylphosphonate

Product 1

HCID 768188402-[5-Ethynyl-1-(2-trimethylsilanyl-ethoxymethyl)-1H-imidazol-2-yl]-pyrrolidine-1-carboxylic acid tert-butyl ester

Sources & evidence

ORD record
ord-8578f32dc885439b8e62fd5506eb12d5
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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