1-Methylimidazole → 2-Fluoro-4-(hydroxy(1-methyl-1h-imidazol-5-yl)methyl)benzonitrile
Reaction equation
[CH2:36]1[O:37][CH2:38][CH2:39][CH2:40]1.[CH2:7]([Li:8])[CH2:9][CH2:10][CH3:11].[CH3:1][n:2]1[cH:3][n:4][cH:5][cH:6]1.[CH:20]([Li:21])([CH2:22][CH3:23])[CH3:24].[Cl:12][Si:13]([CH2:14][CH3:15])([CH2:16][CH3:17])[CH2:18][CH3:19].[F:25][c:26]1[c:27]([C:28]#[N:29])[cH:30][cH:31][c:32]([CH:34]=[O:35])[cH:33]1>>[CH3:1][n:2]1[cH:3][n:4][cH:5][c:6]1[CH:34]([c:32]1[cH:31][cH:30][c:27]([C:28]#[N:29])[c:26]([F:25])[cH:33]1)[OH:35]Participants
7
Sources & evidence
- ORD record
- ord-28b04abe2eee4f90b16d3b7dc430fec4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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