Ethanol → 2-chloro-5-methyl-N-(5-methyl-1H-pyrazol-3-yl)pyrimidin-4-amine

HRID 1551906Notes

Reaction equation

HRID 1551906 reaction equation
[CH3:10][c:11]1[cH:12][c:13]([NH2:16])[n:14][nH:15]1.[CH3:26][CH2:27][OH:28].[CH:17]([N:18]([CH2:19][CH3:20])[CH:21]([CH3:22])[CH3:23])([CH3:24])[CH3:25].[Cl:1][c:2]1[n:3][cH:4][c:5]([CH3:9])[c:6]([Cl:8])[n:7]1>>[Cl:1][c:2]1[n:3][cH:4][c:5]([CH3:9])[c:6]([NH:16][c:13]2[cH:12][c:11]([CH3:10])[nH:15][n:14]2)[n:7]1

Participants

5

Reactant 4

HCID 702EthanolHCID 74508Pyrimidine, 2,4-dichloro-5-methyl-HCID 81531DiisopropylethylamineHCID 931461H-Pyrazol-3-amine, 5-methyl-

Product 1

HCID 509936432-chloro-5-methyl-N-(5-methyl-1H-pyrazol-3-yl)pyrimidin-4-amine

Sources & evidence

ORD record
ord-3d0098f8e1ad44ae8b7b8ad9fad1c989
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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