Dichloromethane → 2-Chloro-N-[2-(4-methoxy-phenylamino)-pyrimidin-5-yl]-5-(3-trifluoromethyl-benzoylamino)-benzamide

HRID 1551982Notes

Reaction equation

HRID 1551982 reaction equation
[CH3:35][N:36]1[CH2:37][CH2:38][O:39][CH2:40][CH2:41]1.[CH3:42][O:43][c:44]1[cH:45][cH:46][c:47]([NH:50][c:51]2[n:52][cH:53][c:54]([NH2:57])[cH:55][n:56]2)[cH:48][cH:49]1.[Cl:1][c:2]1[c:3]([C:4](=[O:5])[OH:6])[cH:7][c:8]([NH:11][C:12]([c:13]2[cH:14][c:15]([C:19]([F:20])([F:21])[F:22])[cH:16][cH:17][cH:18]2)=[O:23])[cH:9][cH:10]1.[Cl:24][c:25]1[n:26][c:27]([O:28][CH3:29])[n:30][c:31]([O:32][CH3:33])[n:34]1.[Cl:58][CH2:59][Cl:60]>>[Cl:1][c:2]1[c:3]([C:4](=[O:6])[NH:57][c:54]2[cH:53][n:52][c:51]([NH:50][c:47]3[cH:46][cH:45][c:44]([O:43][CH3:42])[cH:49][cH:48]3)[n:56][cH:55]2)[cH:7][c:8]([NH:11][C:12]([c:13]2[cH:14][c:15]([C:19]([F:20])([F:21])[F:22])[cH:16][cH:17][cH:18]2)=[O:23])[cH:9][cH:10]1

Participants

6

Reactant 5

HCID 6344DichloromethaneHCID 79724-MethylmorpholineHCID 184502-Chloro-4,6-dimethoxy-1,3,5-triazineHCID 534011722-Chloro-5-(3-(trifluoromethyl)benzamido)benzoic acidHCID 59652746N2-(4-Methoxyphenyl)pyrimidine-2,5-diamine

Product 1

HCID 249629092-Chloro-N-[2-(4-methoxy-phenylamino)-pyrimidin-5-yl]-5-(3-trifluoromethyl-benzoylamino)-benzamide

Sources & evidence

ORD record
ord-4c0c155ef5bc44c8a59074e39e1f70df
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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