Bromide ion → 5-[2-Benzyloxy-4-(hydroxypyridin-2-yl-methyl)-phenyl]1,1-dioxo-2-(2-trimethylsilanylethyl)-1,2,5-thiadiazolidin-3-one

HRID 1552166Notes

Reaction equation

HRID 1552166 reaction equation
[Br-:31].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[cH:10][c:11]([CH:12]=[O:13])[cH:14][cH:15][c:16]1[N:17]1[S:18](=[O:29])(=[O:30])[N:19]([CH2:23][CH2:24][Si:25]([CH3:26])([CH3:27])[CH3:28])[C:20](=[O:22])[CH2:21]1.[CH2:39]1[O:40][CH2:41][CH2:42][CH2:43]1.[n:32]1[c:33]([Mg+:38])[cH:34][cH:35][cH:36][cH:37]1>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[cH:10][c:11]([CH:12]([OH:13])[c:33]2[n:32][cH:37][cH:36][cH:35][cH:34]2)[cH:14][cH:15][c:16]1[N:17]1[S:18](=[O:29])(=[O:30])[N:19]([CH2:23][CH2:24][Si:25]([CH3:26])([CH3:27])[CH3:28])[C:20](=[O:22])[CH2:21]1

Participants

5

Reactant 4

HCID 259Bromide ionHCID 8028TetrahydrofuranHCID 866250473-Benzyloxy-4-[1,1,4-trioxo-5-(2-trimethylsilanylethyl)-1,2,5-thiadiazolidin-2-yl]-benzaldehydeHCID 178507014HCID 178507014, compound

Product 1

HCID 688429995-[2-Benzyloxy-4-(hydroxypyridin-2-yl-methyl)-phenyl]1,1-dioxo-2-(2-trimethylsilanylethyl)-1,2,5-thiadiazolidin-3-one

Sources & evidence

ORD record
ord-3e379bf50a1d41c381eaf8dbb81203f3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

Loading…