Dimethylamine → 2-[3-(3-Hydroxy-5-methylphenyl)-4-[2-(3-hydroxypyrrolidin-1-yl)pyrimidin-4-yl]pyrazol-1-yl]acetonitrile
Reaction equation
[B:33]([Br:34])([Br:35])[Br:36].[CH3:37][NH:38][CH3:39].[CH3:40][CH2:41][O:42][C:43](=[O:44])[CH3:45].[Cl:1][CH2:2][Cl:3].[OH2:46].[OH:4][CH:5]1[CH2:6][N:7]([c:10]2[n:11][cH:12][cH:13][c:14](-[c:16]3[c:17](-[c:24]4[cH:25][c:26]([O:31][CH3:32])[cH:27][c:28]([CH3:30])[cH:29]4)[n:18][n:19]([CH2:21][C:22]#[N:23])[cH:20]3)[n:15]2)[CH2:8][CH2:9]1>>[OH:4][CH:5]1[CH2:6][N:7]([c:10]2[n:11][cH:12][cH:13][c:14](-[c:16]3[c:17](-[c:24]4[cH:25][c:26]([OH:31])[cH:27][c:28]([CH3:30])[cH:29]4)[n:18][n:19]([CH2:21][C:22]#[N:23])[cH:20]3)[n:15]2)[CH2:8][CH2:9]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-1b752b72b8e84a5ca7a9c81d13d04c47
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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