Bicarbonate Ion → tert-Butyl 2-chloro-6-formylisonicotinate

HRID 1552234Notes

Reaction equation

HRID 1552234 reaction equation
[C:23](=[O:24])([OH:25])[O-:26].[CH2:28]1[O:29][CH2:30][CH2:31][CH2:32]1.[Cl:1][c:2]1[cH:3][c:4]([C:5](=[O:6])[O:7][C:8]([CH3:9])([CH3:10])[CH3:11])[cH:12][c:13]([CH:15]=[CH2:16])[n:14]1.[I+3:17]([O-:18])([O-:19])([O-:20])[O-:21].[Na+:22].[Na+:27].[OH2:33]>>[Cl:1][c:2]1[cH:3][c:4]([C:5](=[O:6])[O:7][C:8]([CH3:9])([CH3:10])[CH3:11])[cH:12][c:13]([CH:15]=[O:18])[n:14]1

Participants

7

Reactant 6

HCID 769Bicarbonate IonHCID 923Sodium ion2×HCID 962WaterHCID 8028TetrahydrofuranHCID 167232PeriodateHCID 86657031tert-Butyl 2-chloro-6-vinylisonicotinate

Product 1

HCID 86657032tert-Butyl 2-chloro-6-formylisonicotinate

Sources & evidence

ORD record
ord-65d7e4e12e0841bf973d118ce0fce5e8
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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