Bromide ion → Methyl 8-(2-benzyloxyphenyl)-6-(4-methoxycarbonylbenzyl)-7-octenoate

HRID 1552450Notes

Reaction equation

HRID 1552450 reaction equation
[Br-:1].[CH2:2]([c:3]1[cH:4][cH:5][cH:6][cH:7][cH:8]1)[O:9][c:10]1[c:11]([CH2:12][P+:13]([c:14]2[cH:15][cH:16][cH:17][cH:18][cH:19]2)([c:20]2[cH:21][cH:22][cH:23][cH:24][cH:25]2)[c:26]2[cH:27][cH:28][cH:29][cH:30][cH:31]2)[cH:32][cH:33][cH:34][cH:35]1.[CH2:89]1[O:90][CH2:91][CH2:92][CH2:93]1.[CH:41](=[O:42])[CH:43]([CH2:44][CH2:45][CH2:46][CH2:47][C:48](=[O:49])[O:50][CH3:51])[CH2:52][c:53]1[cH:54][cH:55][c:56]([C:59](=[O:60])[O:61][CH3:62])[cH:57][cH:58]1.[Cl:77][CH2:78][c:79]1[cH:80][cH:81][c:82]([C:83]([O:84][CH3:85])=[O:86])[cH:87][cH:88]1.[Li:36][CH2:37][CH2:38][CH2:39][CH3:40].[O:63]=[C:64]1[CH2:65][CH2:66][CH2:67][CH2:68][CH:69]1[C:70]([O:71][C:72]([CH3:73])([CH3:74])[CH3:75])=[O:76].[OH2:94]>>[CH2:2]([c:3]1[cH:4][cH:5][cH:6][cH:7][cH:8]1)[O:9][c:10]1[c:11]([CH:12]=[CH:41][CH:43]([CH2:44][CH2:45][CH2:46][CH2:47][C:48](=[O:49])[O:50][CH3:51])[CH2:52][c:53]2[cH:54][cH:55][c:56]([C:59](=[O:60])[O:61][CH3:62])[cH:57][cH:58]2)[cH:32][cH:33][cH:34][cH:35]1

Participants

9

Reactant 8

HCID 259Bromide ionHCID 962WaterHCID 8028TetrahydrofuranHCID 36664Methyl 4-(chloromethyl)benzoateHCID 11255212Methyl 6-formyl-7-(4-methoxycarbonylphenyl)heptanoateHCID 11410110Triphenyl-[(2-phenylmethoxyphenyl)methyl]phosphaniumHCID 12431017tert-Butyl 2-oxocyclohexane-1-carboxylateHCID 178418339Butyllithium

Product 1

HCID 69632062Methyl 8-(2-benzyloxyphenyl)-6-(4-methoxycarbonylbenzyl)-7-octenoate

Sources & evidence

ORD record
ord-996fb204686a48c79b5bc7b7ccc18d2c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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