N-methyl-2-pyrrolidone → N-{3-[6-(6-Amino-pyridin-3-yl)-2-morpholin-4-yl-pyrimidin-4-yl]pyridin-2-yl}-methanesulfonamide
Reaction equation
[C:32](=[O:33])([O-:34])[O-:35].[CH3:27][S:28](=[O:29])(=[O:30])[NH2:31].[CH3:38][N:39]1[CH2:40][CH2:41][CH2:42][C:43]1=[O:44].[Cs+:36].[Cs+:37].[F:1][c:2]1[n:3][cH:4][cH:5][cH:6][c:7]1-[c:8]1[cH:9][c:10](-[c:20]2[cH:21][cH:22][c:23]([NH2:26])[n:24][cH:25]2)[n:11][c:12]([N:14]2[CH2:15][CH2:16][O:17][CH2:18][CH2:19]2)[n:13]1>>[c:2]1([NH:31][S:28]([CH3:27])(=[O:29])=[O:30])[n:3][cH:4][cH:5][cH:6][c:7]1-[c:8]1[cH:9][c:10](-[c:20]2[cH:21][cH:22][c:23]([NH2:26])[n:24][cH:25]2)[n:11][c:12]([N:14]2[CH2:15][CH2:16][O:17][CH2:18][CH2:19]2)[n:13]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-f53f454dafa444919530150edf3368f0
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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