Tetrahydrofuran → Methyl 2-chloro-4-ethynylbenzoate

HRID 1552900Notes

Reaction equation

HRID 1552900 reaction equation
[CH2:36]1[O:37][CH2:38][CH2:39][CH2:40]1.[CH3:19][CH2:20][CH2:21][CH2:22][N+:23]([CH2:24][CH2:25][CH2:26][CH3:27])([CH2:28][CH2:29][CH2:30][CH3:31])[CH2:32][CH2:33][CH2:34][CH3:35].[CH3:1][O:2][C:3]([c:4]1[c:5]([Cl:16])[cH:6][c:7]([C:10]#[C:11][Si:12]([CH3:13])([CH3:14])[CH3:15])[cH:8][cH:9]1)=[O:17].[F-:18]>>[CH3:1][O:2][C:3]([c:4]1[c:5]([Cl:16])[cH:6][c:7]([C:10]#[CH:11])[cH:8][cH:9]1)=[O:17]

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 16028TetrabutylammoniumHCID 28179Fluoride IonHCID 673682802-Chloro-4-trimethylsilanylethynyl-benzoic acid methyl ester

Product 1

HCID 71306162Methyl 2-chloro-4-ethynylbenzoate

Sources & evidence

ORD record
ord-fd77740438fc4a7ca36fd2ab654846f2
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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