Dimethylformamide → 6-(Benzyloxy)-4-chloropyrido[3,4-d]pyrimidine

HRID 1553661Notes

Reaction equation

HRID 1553661 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[cH:10][c:11]2[c:12]([n:13][cH:14][n:15][c:16]2[OH:17])[cH:18][n:19]1.[O:20]=[CH:21][N:22]([CH3:23])[CH3:24].[S:25]([Cl:26])([Cl:27])=[O:28]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[cH:10][c:11]2[c:12]([n:13][cH:14][n:15][c:16]2[Cl:27])[cH:18][n:19]1

Participants

4

Reactant 3

HCID 6228DimethylformamideHCID 24386Thionyl ChlorideHCID 1785180356-phenylmethoxy-1H-pyrido[3,4-d]pyrimidin-4-one

Product 1

HCID 227274286-(Benzyloxy)-4-chloropyrido[3,4-d]pyrimidine

Sources & evidence

ORD record
ord-a5f13e39a7e546fe92bea8287f6e151f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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