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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 15537Generated: October 29, 2026

(4-Nitro-2-propyl-benzoimidazol-1-yl)-acetic acid tert-butyl ester → (4-Amino-2-propyl-benzoimidazol-1-yl)-acetic acid tert-butyl ester

https://huagongshe.com/reaction/15537

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(4-Nitro-2-propyl-benzoimidazol-1-yl)-acetic acid tert-butyl esterHCID 67200283—
CatalystPalladiumHCID 23938—
Product(4-Amino-2-propyl-benzoimidazol-1-yl)-acetic acid tert-butyl esterHCID 67201653—

Reaction Steps

The sub-title compound was prepared by the method of example 1, step c.) using (4-nitro-2-propyl-benzoimidazol-1-yl)-acetic acid tert-butyl ester (regioisomer 2) from step b.) and 10% Pd/C and was used in crude form without purification. MS: ESI (positive): 290 (M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07732618B2
Source datasetuspto-grants-2010_06
ORD IDord-157e01ed52c84621a5044a9ce246d734
Source noteuspto-grants-2010_06