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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1553716Generated: October 31, 2026

Tetrahydrofuran → 8-Hydroxy-8-(6-methoxy-3-pyridyl)-1,4-dioxaspiro[4.5]decane

https://huagongshe.com/reaction/1553716

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
Reactant1,4-Dioxaspiro[4.5]decan-8-oneHCID 567415—
Reactant5-Bromo-2-methoxypyridineHCID 2734895—
ReactantButyllithiumHCID 178418339—
Product8-Hydroxy-8-(6-methoxy-3-pyridyl)-1,4-dioxaspiro[4.5]decaneHCID 59556066—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (1/10)
ORD IDord-f2009095b0784d9c924eabab9f1e906d
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (1/10)