Tetrahydrofuran → 8-Hydroxy-8-(6-methoxy-3-pyridyl)-1,4-dioxaspiro[4.5]decane
Reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([O:8][CH3:9])[n:6][cH:7]1.[CH2:26]1[O:27][CH2:28][CH2:29][CH2:30]1.[CH3:10][CH2:11][CH2:12][CH2:13][Li:14].[O:15]1[CH2:16][CH2:17][O:18][C:19]12[CH2:20][CH2:21][C:22](=[O:25])[CH2:23][CH2:24]2>>[c:2]1([C:22]2([OH:25])[CH2:21][CH2:20][C:19]3([O:15][CH2:16][CH2:17][O:18]3)[CH2:24][CH2:23]2)[cH:3][cH:4][c:5]([O:8][CH3:9])[n:6][cH:7]1Participants
5
Sources & evidence
- ORD record
- ord-f2009095b0784d9c924eabab9f1e906d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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