Borane → tert-Butyl 4-aminomethyl-4-fluoropiperidine-1-carboxylate
Reaction equation
[BH3:17].[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][C:11]([F:14])([C:15]#[N:16])[CH2:12][CH2:13]1.[CH2:18]1[O:19][CH2:20][CH2:21][CH2:22]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][C:11]([F:14])([CH2:15][NH2:16])[CH2:12][CH2:13]1Participants
4
Sources & evidence
- ORD record
- ord-fba1a3b7283144f8a734b33e405d09c7
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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