Tetrahydrofuran → 6-(4-(3-tert.-Butoxycarbonyl-thiazolidin-2-yl-carbonyl-amino)-phenyl)-5-methyl-4,5-dihydro-3(2H)-pyridazinone

HRID 1553878Notes

Reaction equation

HRID 1553878 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]([C:13](=[O:14])[OH:15])[S:10][CH2:11][CH2:12]1.[NH2:16][c:17]1[cH:18][cH:19][c:20]([C:23]2=[N:28][NH:27][C:26](=[O:29])[CH2:25][CH:24]2[CH3:30])[cH:21][cH:22]1.[O:31]1[CH2:32][CH2:33][CH2:34][CH2:35]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]([C:13](=[O:15])[NH:16][c:17]2[cH:18][cH:19][c:20]([C:23]3=[N:28][NH:27][C:26](=[O:29])[CH2:25][CH:24]3[CH3:30])[cH:21][cH:22]2)[S:10][CH2:11][CH2:12]1

Participants

4

Reactant 3

HCID 8028TetrahydrofuranHCID 161928Ici 109,081HCID 46440943-(tert-Butoxycarbonyl)-1,3-thiazolidine-2-carboxylic acid

Product 1

HCID 137494526-(4-(3-tert.-Butoxycarbonyl-thiazolidin-2-yl-carbonyl-amino)-phenyl)-5-methyl-4,5-dihydro-3(2H)-pyridazinone

Sources & evidence

ORD record
ord-1ff4d7eb885f4604bbe055778a978e27
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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