Hydrochloric Acid → N-(3-azabicyclo[3.1.0]hexan-2-ylmethyl)-5-bromopyrimidin-2-amine

HRID 1553933Notes

Reaction equation

HRID 1553933 reaction equation
[C:2]([O:3][C:4](=[O:5])[N:9]1[CH:10]([CH2:15][NH:16][c:17]2[n:18][cH:19][c:20]([Br:23])[cH:21][n:22]2)[CH:11]2[CH2:12][CH:13]2[CH2:14]1)([CH3:6])([CH3:7])[CH3:8].[ClH:1].[O:24]1[CH2:25][CH2:26][O:27][CH2:28][CH2:29]1>>[NH:9]1[CH:10]([CH2:15][NH:16][c:17]2[n:18][cH:19][c:20]([Br:23])[cH:21][n:22]2)[CH:11]2[CH2:12][CH:13]2[CH2:14]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 312751,4-DioxaneHCID 68445839Tert-butyl 2-[[(5-bromopyrimidin-2-yl)amino]methyl]-3-azabicyclo[3.1.0]hexane-3-carboxylate

Product 1

HCID 57489334N-(3-azabicyclo[3.1.0]hexan-2-ylmethyl)-5-bromopyrimidin-2-amine

Sources & evidence

ORD record
ord-ccda08f177594d2baa5c5df194ef6e8e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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