HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1554182Generated: November 2, 2026
Tetrahydrofuran → 4-[1-[6-(2,4-Difluorophenyl)pyridin-2-yl]-2-oxo-4-(trimethylsilyl)but-3-yn-1-yl]-3,5-difluorobenzonitrile
https://huagongshe.com/reaction/1554182
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Tetrahydrofuran | HCID 8028 | — |
| Reactant | Lithium ion | HCID 28486 | — |
| Reactant | Ethyl 3-(trimethylsilyl)propynoate | HCID 568601 | — |
| Reactant | Npc316347 | HCID 3280088 | — |
| Reactant | 4-{[6-(2,4-Difluorophenyl)pyridin-2-yl]methyl}-3,5-difluorobenzonitrile | HCID 57700378 | — |
| Product | 4-[1-[6-(2,4-Difluorophenyl)pyridin-2-yl]-2-oxo-4-(trimethylsilyl)but-3-yn-1-yl]-3,5-difluorobenzonitrile | HCID 57700365 | — |
Provenance & Evidence
| DOI | 10.1039/C8SC04228D |
|---|
| Source dataset | Training data from https://doi.org/10.1039/C8SC04228D (1/10) |
|---|
| ORD ID | ord-4376dc3f8494432abd4f6ce8991197cb |
|---|
| Source note | Training data from https://doi.org/10.1039/C8SC04228D (1/10) |
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