Dimethylamine → 1-[3,5-dichloro-4-(3,8-dihydroimidazo[4,5-d]dipyrido[2,3-b: 4',3'-f]azepin-2-yl)phenyl]-N,N-dimethylmethanamine

HRID 1554306Notes

Reaction equation

HRID 1554306 reaction equation
[CH3:1][NH:2][CH3:3].[CH3:34][N:35]([CH3:36])[CH:37]=[O:38].[CH3:39][OH:40].[Cl:6][c:7]1[c:8](-[c:16]2[nH:17][c:18]3[c:19]([n:33]2)-[c:20]2[c:21]([n:29][cH:30][cH:31][cH:32]2)[NH:22][c:23]2[c:24]-3[cH:25][cH:26][n:27][cH:28]2)[c:9]([Cl:15])[cH:10][c:11]([CH2:13][Cl:14])[cH:12]1.[H-:4].[Na+:5]>>[CH3:1][N:2]([CH3:3])[CH2:13][c:11]1[cH:10][c:9]([Cl:15])[c:8](-[c:16]2[nH:17][c:18]3[c:19]([n:33]2)-[c:20]2[c:21]([n:29][cH:30][cH:31][cH:32]2)[NH:22][c:23]2[c:24]-3[cH:25][cH:26][n:27][cH:28]2)[c:7]([Cl:6])[cH:12]1

Participants

7

Reactant 6

HCID 674DimethylamineHCID 887MethanolHCID 923Sodium ionHCID 6228DimethylformamideHCID 166653HydrideHCID 66887168HCID 66887168, compound

Product 1

HCID 160720251-[3,5-dichloro-4-(3,8-dihydroimidazo[4,5-d]dipyrido[2,3-b: 4',3'-f]azepin-2-yl)phenyl]-N,N-dimethylmethanamine

Sources & evidence

ORD record
ord-16db019147d4441598324fab2dd6397d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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