Glycinamide → N-(1-amino-1-oxopropan-2-yl)-3-[5-chloro-4-[(2,4-difluorophenyl)methoxy]-6-oxopyrimidin-1-yl]-4-methylbenzamide

HRID 1554446Notes

Reaction equation

HRID 1554446 reaction equation
[Cl:1][c:2]1[c:3]([O:23][CH2:24][c:25]2[c:26]([F:32])[cH:27][c:28]([F:31])[cH:29][cH:30]2)[n:4][cH:5][n:6](-[c:9]2[cH:10][c:11]([C:12](=[O:13])[NH:14][CH2:15][C:16](=[O:17])[NH2:18])[cH:19][cH:20][c:21]2[CH3:22])[c:7]1=[O:8].[NH2:33][CH:34]([C:35]([NH2:36])=[O:37])[CH3:38].[NH2:39][CH2:40][C:41]([NH2:42])=[O:43]>>[Cl:1][c:2]1[c:3]([O:23][CH2:24][c:25]2[c:26]([F:32])[cH:27][c:28]([F:31])[cH:29][cH:30]2)[n:4][cH:5][n:6](-[c:9]2[cH:10][c:11]([C:12](=[O:13])[NH:14][CH:15]([C:16](=[O:17])[NH2:18])[CH3:34])[cH:19][cH:20][c:21]2[CH3:22])[c:7]1=[O:8]

Participants

4

Reactant 3

HCID 69020GlycinamideHCID 3502872-AminopropanamideHCID 210890083-[5-chloro-4-[(2,4-difluorobenzyl)oxy)-6-oxopyrimidin-1(6H)-yl]-N-[1-(aminocarbonyl)methyl]-4-methylbenzamide

Product 1

HCID 21089026N-(1-amino-1-oxopropan-2-yl)-3-[5-chloro-4-[(2,4-difluorophenyl)methoxy]-6-oxopyrimidin-1-yl]-4-methylbenzamide

Sources & evidence

ORD record
ord-33cc17744e064da4aa8b40b80b1b55f1
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

Loading…