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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1554823Generated: October 31, 2026

Dimethylformamide → (4'-{4-[4-(Propane-1-sulfonyl)-piperazin-1-ylmethyl]-phenylcarbamoyl}-6-trifluoromethoxy-biphenyl-3-yl)-carbamic acid tert-butyl ester

https://huagongshe.com/reaction/1554823

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
Reactant4-MethylmorpholineHCID 7972—
Reactant1-Ethyl-3-(3'-dimethylaminopropyl)carbodiimideHCID 15908—
Reactant1-HydroxybenzotriazoleHCID 75771—
Reactant4-[(4-(Propylsulfonyl)piperazin-1-yl)methyl]anilineHCID 28273548—
Reactant5'-tert-Butoxycarbonylamino-2'-trifluoromethoxy-biphenyl-4-carboxylic acidHCID 59822341—
Product(4'-{4-[4-(Propane-1-sulfonyl)-piperazin-1-ylmethyl]-phenylcarbamoyl}-6-trifluoromethoxy-biphenyl-3-yl)-carbamic acid tert-butyl esterHCID 59822362—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (1/10)
ORD IDord-6e88763359b34d2bb06e4f1cefa16dd6
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (1/10)