Dichloromethane → 3,3-dimethyl-4-oxo-4-[2-(3,4,5-trimethoxy-phenyl)-5H-pyrrolo[2,3-b]pyrazin-7-yl]-butyronitrile
Reaction equation
[CH3:1][C:2]([CH2:3][C:4]#[N:5])([C:6]([c:7]1[cH:8][n:9]([Si:28]([CH:29]([CH3:30])[CH3:31])([CH:32]([CH3:33])[CH3:34])[CH:35]([CH3:36])[CH3:37])[c:10]2[n:11][cH:12][c:13](-[c:16]3[cH:17][c:18]([O:26][CH3:27])[c:19]([O:24][CH3:25])[c:20]([O:22][CH3:23])[cH:21]3)[n:14][c:15]12)=[O:38])[CH3:39].[Cl:47][CH2:48][Cl:49].[OH:40][C:41]([C:42]([F:43])([F:44])[F:45])=[O:46]>>[CH3:1][C:2]([CH2:3][C:4]#[N:5])([C:6]([c:7]1[cH:8][nH:9][c:10]2[n:11][cH:12][c:13](-[c:16]3[cH:17][c:18]([O:26][CH3:27])[c:19]([O:24][CH3:25])[c:20]([O:22][CH3:23])[cH:21]3)[n:14][c:15]12)=[O:38])[CH3:39]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-d73c2862fe884dd58dd1776d71a22d01
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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