Toluene → 9-tert-butyl-3-methoxy-2,14-di-1,3-thiazol-5-yl-5,6,10,11-tetrahydro-9H-[1,4]oxazocino[7',6':4,5]pyrrolo[2,1-a]isoquinolin-8(13H)-one
Reaction equation
[Br:1][c:2]1[c:3]([O:31][CH3:32])[cH:4][c:5]2[c:10]([cH:11]1)-[c:9]1[n:8]([c:14]3[c:13]([c:12]1-[c:26]1[cH:27][n:28][cH:29][s:30]1)[CH2:20][O:19][CH2:18][CH2:17][N:16]([C:21]([CH3:22])([CH3:23])[CH3:24])[C:15]3=[O:25])[CH2:7][CH2:6]2.[C:51]([O:52][CH2:53][CH3:54])(=[O:55])[CH3:56].[CH2:33]([Sn:34]([CH2:35][CH2:36][CH2:37][CH3:43])([c:38]1[cH:39][n:40][cH:41][s:42]1)[CH2:44][CH2:45][CH2:46][CH3:47])[CH2:48][CH2:49][CH3:50].[CH3:57][CH2:58][CH2:59][CH2:60][CH2:61][CH2:62][CH3:63].[CH3:64][c:65]1[cH:66][cH:67][cH:68][cH:69][cH:70]1.[cH:71]1[cH:72][cH:73][c:74]([P:75]([Pd:76]([P:77]([c:78]2[cH:79][cH:80][cH:81][cH:82][cH:83]2)([c:84]2[cH:85][cH:86][cH:87][cH:88][cH:89]2)[c:90]2[cH:91][cH:92][cH:93][cH:94][cH:95]2)([P:96]([c:97]2[cH:98][cH:99][cH:100][cH:101][cH:102]2)([c:103]2[cH:104][cH:105][cH:106][cH:107][cH:108]2)[c:109]2[cH:110][cH:111][cH:112][cH:113][cH:114]2)[P:115]([c:116]2[cH:117][cH:118][cH:119][cH:120][cH:121]2)([c:122]2[cH:123][cH:124][cH:125][cH:126][cH:127]2)[c:128]2[cH:129][cH:130][cH:131][cH:132][cH:133]2)([c:134]2[cH:135][cH:136][cH:137][cH:138][cH:139]2)[c:140]2[cH:141][cH:142][cH:143][cH:144][cH:145]2)[cH:146][cH:147]1>>[c:2]1(-[c:38]2[cH:39][n:40][cH:41][s:42]2)[c:3]([O:31][CH3:32])[cH:4][c:5]2[c:10]([cH:11]1)-[c:9]1[n:8]([c:14]3[c:13]([c:12]1-[c:26]1[cH:27][n:28][cH:29][s:30]1)[CH2:20][O:19][CH2:18][CH2:17][N:16]([C:21]([CH3:22])([CH3:23])[CH3:24])[C:15]3=[O:25])[CH2:7][CH2:6]2Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-b598a937dc754c2bbdc60fad0815b111
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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