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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1555305Generated: November 5, 2026

Tetrahydrofuran → Trifluoro-methanesulfonic acid 3,5-dichloro-4-[1-(4,4-difluoro-cyclohexyl)-2-oxo-pyrrolidin-3-ylmethyl]-phenyl ester

https://huagongshe.com/reaction/1555305

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantLithium ionHCID 28486—
ReactantDiisopropylamideHCID 5062348—
ReactantHCID 57878591HCID 57878591—
ReactantTrifluoro-methanesulfonic acid 3,5-dichloro-4-methanesulfonyloxymethyl-phenyl esterHCID 86634570—
ProductTrifluoro-methanesulfonic acid 3,5-dichloro-4-[1-(4,4-difluoro-cyclohexyl)-2-oxo-pyrrolidin-3-ylmethyl]-phenyl esterHCID 57878605—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (1/10)
ORD IDord-07ad5262f73e403b8582d0c60578bed4
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (1/10)