Dichloromethane → 7-methoxy-5-(N-methylpiperidin-4-yloxy)-3-pivaloyloxymethyl-3,4-dihydroquinazolin-4-one

HRID 1555483노트

반응식

[CH2:66]([Cl:67])[Cl:68].[N:1]([C:2]([O:3][C:4]([CH3:5])([CH3:6])[CH3:7])=[O:8])=[N:9][C:10]([O:11][C:12]([CH3:13])([CH3:14])[CH3:15])=[O:16].[OH:17][c:18]1[c:19]2[c:20](=[O:38])[n:21]([CH2:30][O:31][C:32]([C:33]([CH3:34])([CH3:35])[CH3:36])=[O:37])[cH:22][n:23][c:24]2[cH:25][c:26]([O:28][CH3:29])[cH:27]1.[OH:58][CH:59]1[CH2:60][CH2:61][N:62]([CH3:65])[CH2:63][CH2:64]1.[c:39]1([P:40]([c:41]2[cH:42][cH:43][cH:44][cH:45][cH:46]2)[c:47]2[cH:48][cH:49][cH:50][cH:51][cH:52]2)[cH:53][cH:54][cH:55][cH:56][cH:57]1>>[O:17]([c:18]1[c:19]2[c:20](=[O:38])[n:21]([CH2:30][O:31][C:32]([C:33]([CH3:34])([CH3:35])[CH3:36])=[O:37])[cH:22][n:23][c:24]2[cH:25][c:26]([O:28][CH3:29])[cH:27]1)[CH:59]1[CH2:60][CH2:61][N:62]([CH3:65])[CH2:63][CH2:64]1