Dimethylformamide → Methyl 4-chloro-7-methoxyquinoline-6-carboxylate

HRID 1555567Notes

Reaction equation

HRID 1555567 reaction equation
[CH3:1][O:2][c:3]1[c:4]([C:14](=[O:15])[O:16][CH3:17])[cH:5][c:6]2[c:7](=[O:13])[cH:8][cH:9][nH:10][c:11]2[cH:12]1.[O:22]=[CH:23][N:24]([CH3:25])[CH3:26].[S:18]([Cl:19])([Cl:20])=[O:21]>>[CH3:1][O:2][c:3]1[c:4]([C:14](=[O:15])[O:16][CH3:17])[cH:5][c:6]2[c:7]([Cl:20])[cH:8][cH:9][n:10][c:11]2[cH:12]1

Participants

4

Reactant 3

HCID 6228DimethylformamideHCID 24386Thionyl ChlorideHCID 22646623Methyl 1,4-dihydro-7-methoxy-4-oxo-6-quinolinecarboxylate

Product 1

HCID 22646520Methyl 4-chloro-7-methoxyquinoline-6-carboxylate

Sources & evidence

ORD record
ord-3eb4126dc2434be8b923973719f542b8
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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