Trifluoroacetic acid → 4-(6-Chloronaphthalene-2-sulfonyl)-1-{[1-(4-pyridyl)-4-piperidinyl](2,2,2-trifluoroethyl)amino}-2-piperazinone

HRID 1555617Notes

Reaction equation

HRID 1555617 reaction equation
[Cl:1][c:2]1[cH:3][c:4]2[cH:5][cH:6][c:7]([S:12](=[O:13])(=[O:14])[N:15]3[CH2:16][C:17](=[O:34])[N:18]([NH:21][CH:22]4[CH2:23][CH2:24][N:25]([c:28]5[cH:29][cH:30][n:31][cH:32][cH:33]5)[CH2:26][CH2:27]4)[CH2:19][CH2:20]3)[cH:8][c:9]2[cH:10][cH:11]1.[OH:35][C:36](=[O:37])[C:38]([F:39])([F:40])[F:41]>>[Cl:1][c:2]1[cH:3][c:4]2[cH:5][cH:6][c:7]([S:12](=[O:13])(=[O:14])[N:15]3[CH2:16][C:17](=[O:34])[N:18]([N:21]([CH:22]4[CH2:23][CH2:24][N:25]([c:28]5[cH:29][cH:30][n:31][cH:32][cH:33]5)[CH2:26][CH2:27]4)[CH2:36][C:38]([F:39])([F:40])[F:41])[CH2:19][CH2:20]3)[cH:8][c:9]2[cH:10][cH:11]1

Participants

3

Reactant 2

HCID 6422Trifluoroacetic acidHCID 178254104-(6-Chloronaphthalene-2-sulfonyl)-1-[1-(4-pyridyl)-4-piperidinylamino]-2-piperazinone

Product 1

HCID 227272534-(6-Chloronaphthalene-2-sulfonyl)-1-{[1-(4-pyridyl)-4-piperidinyl](2,2,2-trifluoroethyl)amino}-2-piperazinone

Sources & evidence

ORD record
ord-9db707528d7e4c9ca945b46bca6225e2
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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