Water → 1-(5-Amino-3-methyl-2-pyridinyl)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-3-methyl-3-prop-2-enylpiperidin-2-one

HRID 1555626Notes

Reaction equation

HRID 1555626 reaction equation
[CH2:1]([CH:2]=[CH2:3])[C:4]1([CH3:35])[C:5](=[O:34])[N:6]([c:24]2[n:25][cH:26][c:27]([N+:31]([O-:32])=[O:33])[cH:28][c:29]2[CH3:30])[CH:7]([c:17]2[cH:18][cH:19][c:20]([Cl:23])[cH:21][cH:22]2)[CH:8]([c:10]2[cH:11][c:12]([Cl:16])[cH:13][cH:14][cH:15]2)[CH2:9]1.[CH3:41][CH2:42][O:43][C:44](=[O:45])[CH3:46].[OH2:36].[OH2:37].[Sn:38]([Cl:39])[Cl:40]>>[CH2:1]([CH:2]=[CH2:3])[C:4]1([CH3:35])[C:5](=[O:34])[N:6]([c:24]2[n:25][cH:26][c:27]([NH2:31])[cH:28][c:29]2[CH3:30])[CH:7]([c:17]2[cH:18][cH:19][c:20]([Cl:23])[cH:21][cH:22]2)[CH:8]([c:10]2[cH:11][c:12]([Cl:16])[cH:13][cH:14][cH:15]2)[CH2:9]1

Participants

5

Reactant 4

HCID 962Water2×HCID 8857Ethyl AcetateHCID 24479Stannous ChlorideHCID 768348305-(3-Chlorophenyl)-6-(4-chlorophenyl)-3-methyl-1-(3-methyl-5-nitro-2-pyridinyl)-3-prop-2-enylpiperidin-2-one

Product 1

HCID 768345881-(5-Amino-3-methyl-2-pyridinyl)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-3-methyl-3-prop-2-enylpiperidin-2-one

Sources & evidence

ORD record
ord-967498f074bb41b2888e449df44006da
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

Loading…