Dichloromethane → methyl 4-[1-(2,3-dihydro-1H-indole-7-carbonylamino)ethyl]benzoate

HRID 1556006Notes

Reaction equation

HRID 1556006 reaction equation
[CH3:1][O:2][C:3](=[O:4])[c:5]1[cH:6][cH:7][c:8]([CH:11]([CH3:12])[NH:13][C:14](=[O:15])[c:16]2[cH:17][cH:18][cH:19][c:20]3[c:24]2[N:23]([C:25]([O:26][C:27]([CH3:28])([CH3:29])[CH3:30])=[O:31])[CH2:22][CH2:21]3)[cH:9][cH:10]1.[Cl:39][CH2:40][Cl:41].[F:32][C:33]([F:34])([F:35])[C:36]([OH:37])=[O:38]>>[CH3:1][O:2][C:3](=[O:4])[c:5]1[cH:6][cH:7][c:8]([CH:11]([CH3:12])[NH:13][C:14](=[O:15])[c:16]2[cH:17][cH:18][cH:19][c:20]3[c:24]2[NH:23][CH2:22][CH2:21]3)[cH:9][cH:10]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 143593195Tert-butyl 7-[1-(4-methoxycarbonylphenyl)ethylcarbamoyl]-2,3-dihydroindole-1-carboxylate

Product 1

HCID 72265021methyl 4-[1-(2,3-dihydro-1H-indole-7-carbonylamino)ethyl]benzoate

Sources & evidence

ORD record
ord-16cee7ca0b0843668c7dcbfbb8a9dee1
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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