Chloride → ethyl 6-amino-2,2-bisfluoromethyl-2H-1-benzopyran-4-carboxylate

HRID 1556435Notes

Reaction equation

HRID 1556435 reaction equation
[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[C:6]1=[CH:7][C:8]([CH2:19][F:20])([CH2:21][F:22])[O:9][c:10]2[c:11]1[cH:12][c:13]([N+:16]([O-:17])=[O:18])[cH:14][cH:15]2.[CH2:26]([OH:27])[CH3:28].[Cl-:23].[Cl-:25].[Na+:24]>>[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[C:6]1=[CH:7][C:8]([CH2:19][F:20])([CH2:21][F:22])[O:9][c:10]2[c:11]1[cH:12][c:13]([NH2:16])[cH:14][cH:15]2

Participants

5

Reactant 4

HCID 312Chloride2×HCID 702EthanolHCID 923Sodium ionHCID 19037092ethyl 2,2-bisfluoromethyl-6-nitro-2H-1-benzopyran-4-carboxylate

Product 1

HCID 19037020ethyl 6-amino-2,2-bisfluoromethyl-2H-1-benzopyran-4-carboxylate

Sources & evidence

ORD record
ord-50f104199f464db48eaab42093d4c4c4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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