Tetrahydrofuran → 4-(5-(1-aminoethyl)-2-(5-fluoro-6-methoxypyridin-3-ylamino)pyridin-3-yl)-N,N-bis(4-methoxybenzyl)-6-methyl-1,3,5-triazin-2-amine

HRID 1556649Notes

Reaction equation

HRID 1556649 reaction equation
[CH2:48]1[O:49][CH2:50][CH2:51][CH2:52]1.[N:1](=[N+:2]=[N-:3])[CH:4]([CH3:5])[c:6]1[cH:7][c:8](-[c:22]2[n:23][c:24]([N:29]([CH2:30][c:31]3[cH:32][cH:33][c:34]([O:37][CH3:38])[cH:35][cH:36]3)[CH2:39][c:40]3[cH:41][cH:42][c:43]([O:46][CH3:47])[cH:44][cH:45]3)[n:25][c:26]([CH3:28])[n:27]2)[c:9]([NH:12][c:13]2[cH:14][n:15][c:16]([O:20][CH3:21])[c:17]([F:19])[cH:18]2)[n:10][cH:11]1>>[NH2:1][CH:4]([CH3:5])[c:6]1[cH:7][c:8](-[c:22]2[n:23][c:24]([N:29]([CH2:30][c:31]3[cH:32][cH:33][c:34]([O:37][CH3:38])[cH:35][cH:36]3)[CH2:39][c:40]3[cH:41][cH:42][c:43]([O:46][CH3:47])[cH:44][cH:45]3)[n:25][c:26]([CH3:28])[n:27]2)[c:9]([NH:12][c:13]2[cH:14][n:15][c:16]([O:20][CH3:21])[c:17]([F:19])[cH:18]2)[n:10][cH:11]1

Participants

3

Reactant 2

HCID 8028TetrahydrofuranHCID 866470754-(5-(1-azidoethyl)-2-(5-fluoro-6-methoxypyridin-3-ylamino)pyridin-3-yl)-N,N-bis(4-methoxybenzyl)-6-methyl-1,3,5-triazin-2-amine

Product 1

HCID 666120754-(5-(1-aminoethyl)-2-(5-fluoro-6-methoxypyridin-3-ylamino)pyridin-3-yl)-N,N-bis(4-methoxybenzyl)-6-methyl-1,3,5-triazin-2-amine

Sources & evidence

ORD record
ord-d100b648cfa1412ab0783955afc6fdd9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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