Chloride → 2-Amino-5-(3'-chlorobenzyl)benzonitrile
Reaction equation
[Cl-:11].[Cl:12][c:13]1[cH:14][c:15]([CH2:16][Zn+:17])[cH:18][cH:19][cH:20]1.[NH2:1][c:2]1[c:3]([C:4]#[N:5])[cH:6][c:7]([I:10])[cH:8][cH:9]1.[NH2:21][c:22]1[cH:23][cH:24][c:25]([CH2:26][c:27]2[cH:28][cH:29][cH:30][cH:31][cH:32]2)[cH:33][c:34]1[C:35]#[N:36]>>[NH2:1][c:2]1[c:3]([C:4]#[N:5])[cH:6][c:7]([CH2:16][c:15]2[cH:14][c:13]([Cl:12])[cH:20][cH:19][cH:18]2)[cH:8][cH:9]1Participants
5
Sources & evidence
- ORD record
- ord-d7729c70c70946fca3d7c0cfa09c9f64
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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