Dimethyl Sulfoxide → tert-Butyl 4-formylpiperidine-1-carboxylate

HRID 1556846Notes

Reaction equation

HRID 1556846 reaction equation
[C:11](=[O:12])([O:13][C:14]([CH3:15])([CH3:16])[CH3:17])[N:18]1[CH2:19][CH2:20][CH:21]([CH2:24][OH:25])[CH2:22][CH2:23]1.[CH3:29][CH2:30][O:31][CH2:32][CH3:33].[CH3:7][S:8]([CH3:9])=[O:10].[Cl:1][C:2]([C:3]([Cl:4])=[O:5])=[O:6].[Cl:26][CH2:27][Cl:28]>>[C:11](=[O:12])([O:13][C:14]([CH3:15])([CH3:16])[CH3:17])[N:18]1[CH2:19][CH2:20][CH:21]([CH:24]=[O:25])[CH2:22][CH2:23]1

Participants

6

Reactant 5

HCID 679Dimethyl SulfoxideHCID 3283Diethyl EtherHCID 6344DichloromethaneHCID 65578Oxalyl chlorideHCID 2764081Tert-butyl 4-(hydroxymethyl)piperidine-1-carboxylate

Product 1

HCID 1514430tert-Butyl 4-formylpiperidine-1-carboxylate

Sources & evidence

ORD record
ord-5cc2c9cdfd854094abc4d0dab4e03122
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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