Tetrahydrofuran → N-[5-Methyl-6-(4-pyrrolidin-1-yl-piperidine-1-carbonyl)-3-(3-trifluoromethyl-phenyl)-pyridin-2-yl]-methanesulfonamide
Reaction equation
[CH2:58]1[O:59][CH2:60][CH2:61][CH2:62]1.[CH3:1][c:2]1[cH:3][c:4](-[c:30]2[cH:31][c:32]([C:36]([F:37])([F:38])[F:39])[cH:33][cH:34][cH:35]2)[c:5]([N:21]([S:22](=[O:23])(=[O:24])[CH3:25])[S:26]([CH3:27])(=[O:28])=[O:29])[n:6][c:7]1[C:8](=[O:9])[N:10]1[CH2:11][CH2:12][CH:13]([N:16]2[CH2:17][CH2:18][CH2:19][CH2:20]2)[CH2:14][CH2:15]1.[CH3:41][CH2:42][CH2:43][CH2:44][N+:45]([CH2:46][CH2:47][CH2:48][CH3:49])([CH2:50][CH2:51][CH2:52][CH3:53])[CH2:54][CH2:55][CH2:56][CH3:57].[F-:40]>>[CH3:1][c:2]1[cH:3][c:4](-[c:30]2[cH:31][c:32]([C:36]([F:37])([F:38])[F:39])[cH:33][cH:34][cH:35]2)[c:5]([NH:21][S:22](=[O:23])(=[O:24])[CH3:25])[n:6][c:7]1[C:8](=[O:9])[N:10]1[CH2:11][CH2:12][CH:13]([N:16]2[CH2:17][CH2:18][CH2:19][CH2:20]2)[CH2:14][CH2:15]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-66c4c87cdd2145a69d7d72ae56605ec8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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