Dichloromethane → 2-[2-(5-Fluoro-2-methoxyphenyl)-2-methylpropyl]-2-trifluoromethyloxirane

HRID 1557448Notes

Reaction equation

[CH3:1][CH2:2][N:3]([CH2:4][CH3:5])[CH2:6][CH3:7].[CH3:29][S:30](=[O:31])(=[O:32])[Cl:33].[Cl:34][CH2:35][Cl:36].[F:8][c:9]1[cH:10][cH:11][c:12]([O:27][CH3:28])[c:13]([C:15]([CH2:16][C:17]([CH2:18][OH:19])([OH:20])[C:21]([F:22])([F:23])[F:24])([CH3:25])[CH3:26])[cH:14]1>>[F:8][c:9]1[cH:10][cH:11][c:12]([O:27][CH3:28])[c:13]([C:15]([CH2:16][C:17]2([C:21]([F:22])([F:23])[F:24])[CH2:18][O:20]2)([CH3:25])[CH3:26])[cH:14]1

Participants

Reactant 4

HCID 6344Dichloromethane

HCID 8471Triethylamine

HCID 31297Methanesulfonyl chloride

HCID 219489282-Hydroxy-4-(5-fluoro-2-methoxyphenyl)-4-methyl-2-trifluoromethyl-pentanol

Product 1

HCID 160992392-[2-(5-Fluoro-2-methoxyphenyl)-2-methylpropyl]-2-trifluoromethyloxirane

Sources & evidence

ORD record: ord-e694dd36f93c4ae9952a9f0a0162f4cd
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (1/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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