Methanol → 4-((3-Bromo-5-(trifluoromethyl)benzyloxy)methyl)-4-(2,4-difluorophenyl)-1-methylpiperidine
Reaction equation
[Br:1][c:2]1[cH:3][c:4]([CH2:5][O:6][CH2:7][C:8]2([c:21]3[c:22]([F:28])[cH:23][c:24]([F:27])[cH:25][cH:26]3)[CH2:9][CH2:10][N:11]([C:14]([O:15][C:16]([CH3:17])([CH3:18])[CH3:19])=[O:20])[CH2:12][CH2:13]2)[cH:29][c:30]([C:32]([F:33])([F:34])[F:35])[cH:31]1.[C:36]([O:37][BH-:38]([O:39][C:40](=[O:41])[CH3:42])[O:43][C:44](=[O:45])[CH3:46])(=[O:47])[CH3:48].[CH3:57][OH:58].[F:50][C:51]([F:52])([F:53])[C:54]([OH:55])=[O:56].[Na+:49]>>[Br:1][c:2]1[cH:3][c:4]([CH2:5][O:6][CH2:7][C:8]2([c:21]3[c:22]([F:28])[cH:23][c:24]([F:27])[cH:25][cH:26]3)[CH2:9][CH2:10][N:11]([CH3:14])[CH2:12][CH2:13]2)[cH:29][c:30]([C:32]([F:33])([F:34])[F:35])[cH:31]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-b0236ebb5a22404dbd2de1030ff4b9ae
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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