Triethylamine → 5-bromo-N-[3-[4-(3,4-dichlorophenoxy)piperidin-1-yl]-2-hydroxypropyl]-6-oxo-2-(trifluoromethyl)-1H-pyridine-3-carboxamide
Reaction equation
[Br:1][c:2]1[cH:3][c:4]([C:13](=[O:14])[OH:15])[c:5]([C:9]([F:10])([F:11])[F:12])[nH:6][c:7]1=[O:8].[CH3:40][CH2:41][N:42]([CH2:43][CH3:44])[CH2:45][CH3:46].[NH2:20][CH2:21][CH:22]([CH2:23][N:24]1[CH2:25][CH2:26][CH:27]([O:30][c:31]2[cH:32][c:33]([Cl:38])[c:34]([Cl:37])[cH:35][cH:36]2)[CH2:28][CH2:29]1)[OH:39].[S:16]([Cl:17])([Cl:18])=[O:19]>>[Br:1][c:2]1[cH:3][c:4]([C:13](=[O:15])[NH:20][CH2:21][CH:22]([CH2:23][N:24]2[CH2:25][CH2:26][CH:27]([O:30][c:31]3[cH:32][c:33]([Cl:38])[c:34]([Cl:37])[cH:35][cH:36]3)[CH2:28][CH2:29]2)[OH:39])[c:5]([C:9]([F:10])([F:11])[F:12])[nH:6][c:7]1=[O:8]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-85f6be3b1c644cd1921c831a2de5fb00
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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