Trifluoroacetic acid → Ethyl 1-(6-amino-3,5-difluoropyridin-2-yl)-5-benzylamino-6,7,8-trifluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate
Reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[NH:8][c:9]1[c:10]2[c:11](=[O:45])[c:12]([C:40](=[O:41])[O:42][CH2:43][CH3:44])[cH:13][n:14](-[c:22]3[n:23][c:24]([NH:30][CH2:31][c:32]4[cH:33][cH:34][c:35]([O:36][CH3:37])[cH:38][cH:39]4)[c:25]([F:29])[cH:26][c:27]3[F:28])[c:15]2[c:16]([F:21])[c:17]([F:20])[c:18]1[F:19].[OH:46][C:47]([C:48]([F:49])([F:50])[F:51])=[O:52]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[NH:8][c:9]1[c:10]2[c:11](=[O:45])[c:12]([C:40](=[O:41])[O:42][CH2:43][CH3:44])[cH:13][n:14](-[c:22]3[n:23][c:24]([NH2:30])[c:25]([F:29])[cH:26][c:27]3[F:28])[c:15]2[c:16]([F:21])[c:17]([F:20])[c:18]1[F:19]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-41e2d3e78fb0426ea9163c680e270005
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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