Dimethylformamide → 1,1-Dimethylethyl 4-[(3'-{[({3-[({[1,6-diethyl-4-(tetrahydro-2H-pyran-4-ylamino)-1H-pyrazolo[3,4-b]pyridin-5-yl]methyl}amino)carbonyl]phenyl}carbonyl)amino]methyl}-3-biphenylyl)methyl]-1-piperazinecarboxylate
Reaction equation
[CH2:1]([CH3:2])[n:3]1[n:4][cH:5][c:6]2[c:7]1[n:8][c:9]([CH2:32][CH3:33])[c:10]([CH2:19][NH:20][C:21](=[O:22])[c:23]1[cH:24][c:25]([C:26](=[O:27])[OH:28])[cH:29][cH:30][cH:31]1)[c:11]2[NH:12][CH:13]1[CH2:14][CH2:15][O:16][CH2:17][CH2:18]1.[NH2:34][CH2:35][c:36]1[cH:37][c:38](-[c:42]2[cH:43][c:44]([CH2:48][N:49]3[CH2:50][CH2:51][N:52]([C:55](=[O:56])[O:57][C:58]([CH3:59])([CH3:60])[CH3:61])[CH2:53][CH2:54]3)[cH:45][cH:46][cH:47]2)[cH:39][cH:40][cH:41]1.[O:62]=[CH:63][N:64]([CH3:65])[CH3:66]>>[CH2:1]([CH3:2])[n:3]1[n:4][cH:5][c:6]2[c:7]1[n:8][c:9]([CH2:32][CH3:33])[c:10]([CH2:19][NH:20][C:21](=[O:22])[c:23]1[cH:24][c:25]([C:26](=[O:27])[NH:34][CH2:35][c:36]3[cH:37][c:38](-[c:42]4[cH:43][c:44]([CH2:48][N:49]5[CH2:50][CH2:51][N:52]([C:55](=[O:56])[O:57][C:58]([CH3:59])([CH3:60])[CH3:61])[CH2:53][CH2:54]5)[cH:45][cH:46][cH:47]4)[cH:39][cH:40][cH:41]3)[cH:29][cH:30][cH:31]1)[c:11]2[NH:12][CH:13]1[CH2:14][CH2:15][O:16][CH2:17][CH2:18]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-f8e64447c0fc4a208fba0b83e731f442
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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