1,2-Dichloroethane → 4-(4-Iodo-phenyl)-1-methyl-piperidine-4-carbonitrile
Reaction equation
[C:18]([OH:19])(=[O:20])[CH3:21].[CH2:16]=[O:17].[CH2:22]([Cl:23])[CH2:24][Cl:25].[I:1][c:2]1[cH:3][cH:4][c:5]([C:8]2([C:14]#[N:15])[CH2:9][CH2:10][NH:11][CH2:12][CH2:13]2)[cH:6][cH:7]1.[OH2:26]>>[I:1][c:2]1[cH:3][cH:4][c:5]([C:8]2([C:14]#[N:15])[CH2:9][CH2:10][N:11]([CH3:18])[CH2:12][CH2:13]2)[cH:6][cH:7]1Participants
6
Sources & evidence
- ORD record
- ord-eefb9ff324e44213b6eb897abc461516
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
Loading…