Hydrochloric Acid → Tert-butyl 4-methyl-3-[[[5-(2-trimethylsilylethoxymethyl)pyrrolo[2,3-b]pyrazin-2-yl]amino]carbamoyl]piperidine-1-carboxylate
Reaction equation
[C:21]([CH3:22])([CH3:23])([CH3:24])[O:25][C:26](=[O:27])[N:28]1[CH2:29][CH:30]([C:35](=[O:36])[OH:37])[CH:31]([CH3:34])[CH2:32][CH2:33]1.[CH3:2][Si:3]([CH2:4][CH2:5][O:6][CH2:7][n:8]1[cH:9][cH:10][c:11]2[c:12]1[n:13][cH:14][c:15]([NH:17][NH2:18])[n:16]2)([CH3:19])[CH3:20].[ClH:1]>>[CH3:2][Si:3]([CH2:4][CH2:5][O:6][CH2:7][n:8]1[cH:9][cH:10][c:11]2[c:12]1[n:13][cH:14][c:15]([NH:17][NH:18][C:35]([CH:30]1[CH2:29][N:28]([C:26]([O:25][C:21]([CH3:22])([CH3:23])[CH3:24])=[O:27])[CH2:33][CH2:32][CH:31]1[CH3:34])=[O:36])[n:16]2)([CH3:19])[CH3:20]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-fac9b8676bcf489ea920b6499a1a314a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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