Tetrahydrofuran → N1-cyclohexylmethyl-5-(4-methyl-piperazin-1-yl)-N4-phenyl-benzene-1,2,4-triamine

HRID 155898Notes

Reaction equation

HRID 155898 reaction equation
[CH2:34]1[O:35][CH2:36][CH2:37][CH2:38]1.[CH:1]1([CH2:7][NH:8][c:9]2[cH:10][c:11]([N:25]3[CH2:26][CH2:27][N:28]([CH3:31])[CH2:29][CH2:30]3)[c:12]([NH:18][c:19]3[cH:20][cH:21][cH:22][cH:23][cH:24]3)[cH:13][c:14]2[N+:15]([O-:16])=[O:17])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1.[H:32][H:33]>>[CH:1]1([CH2:7][NH:8][c:9]2[cH:10][c:11]([N:25]3[CH2:26][CH2:27][N:28]([CH3:31])[CH2:29][CH2:30]3)[c:12]([NH:18][c:19]3[cH:20][cH:21][cH:22][cH:23][cH:24]3)[cH:13][c:14]2[NH2:15])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1

Participants

4

Reactant 3

HCID 8028TetrahydrofuranHCID 21061669N4-cyclohexylmethyl-2-(4-methyl-piperazin-1-yl)-5-nitro-N1-phenyl-benzene-1,4-diamineHCID 178418361HCID 178418361, compound

Product 1

HCID 21061668N1-cyclohexylmethyl-5-(4-methyl-piperazin-1-yl)-N4-phenyl-benzene-1,2,4-triamine

Sources & evidence

ORD record
ord-0055433b24c54fc7bc27bc79a5b86f45
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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