Methanol → 1-Benzyl-4-[tert-butoxycarbonyl-(2,4-difluoro-benzyl)-amino]-pyrrolidine-2-carboxylic acid
Reaction equation
[CH3:1][O:2][C:3](=[O:4])[CH:5]1[N:6]([CH2:27][c:28]2[cH:29][cH:30][cH:31][cH:32][cH:33]2)[CH2:7][CH:8]([N:10]([CH2:11][c:12]2[c:13]([F:19])[cH:14][c:15]([F:18])[cH:16][cH:17]2)[C:20](=[O:21])[O:22][C:23]([CH3:24])([CH3:25])[CH3:26])[CH2:9]1.[CH3:36][OH:37].[Li+:35].[OH-:34]>>[O:2]=[C:3]([OH:4])[CH:5]1[N:6]([CH2:27][c:28]2[cH:29][cH:30][cH:31][cH:32][cH:33]2)[CH2:7][CH:8]([N:10]([CH2:11][c:12]2[c:13]([F:19])[cH:14][c:15]([F:18])[cH:16][cH:17]2)[C:20](=[O:21])[O:22][C:23]([CH3:24])([CH3:25])[CH3:26])[CH2:9]1Participants
5
Sources & evidence
- ORD record
- ord-a4021e84a5cb4afa810b6c1958e6bda8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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