Methanol → 3-Amino-1-(3-(trifluoromethyl)-5,6-dihydro(1,2,4)triazolo(4,3-a)pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one
Reaction equation
[CH3:37][OH:38].[H:35][H:36].[O:1]=[C:2]([CH:3]=[C:4]([CH2:5][c:6]1[c:7]([F:14])[cH:8][c:9]([F:13])[c:10]([F:12])[cH:11]1)[NH2:15])[N:16]1[CH2:17][c:18]2[n:19]([c:22]([C:25]([F:26])([F:27])[F:28])[n:23][n:24]2)[CH2:20][CH2:21]1.[OH:29][CH2:30][C:31]([F:32])([F:33])[F:34]>>[O:1]=[C:2]([CH2:3][CH:4]([CH2:5][c:6]1[c:7]([F:14])[cH:8][c:9]([F:13])[c:10]([F:12])[cH:11]1)[NH2:15])[N:16]1[CH2:17][c:18]2[n:19]([c:22]([C:25]([F:26])([F:27])[F:28])[n:23][n:24]2)[CH2:20][CH2:21]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-2f86bd6aa2744935957eba21198f1513
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
Loading…