Toluene → 1-(3-Fluoro-4-(trifluoromethyl)phenyl)-3,4-dihydroisoquinoline
Reaction equation
[CH3:28][c:29]1[cH:30][cH:31][cH:32][cH:33][cH:34]1.[F:1][c:2]1[cH:3][c:4]([C:5](=[O:6])[NH:7][CH2:8][CH2:9][c:10]2[cH:11][cH:12][cH:13][cH:14][cH:15]2)[cH:16][cH:17][c:18]1[C:19]([F:20])([F:21])[F:22].[P:23]([Cl:24])([Cl:25])([Cl:26])=[O:27]>>[F:1][c:2]1[cH:3][c:4]([C:5]2=[N:7][CH2:8][CH2:9][c:10]3[cH:11][cH:12][cH:13][cH:14][c:15]32)[cH:16][cH:17][c:18]1[C:19]([F:20])([F:21])[F:22]Participants
4
Sources & evidence
- ORD record
- ord-a3fd9c31079047d5818bfb149af96456
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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