Dichloromethane → 4-(Piperidin-4-yl)aniline

HRID 1559631Notes

Reaction equation

HRID 1559631 reaction equation
[Cl:28][CH2:29][Cl:30].[F:1][C:2]([F:3])([F:4])[C:5]([OH:6])=[O:7].[NH2:8][c:9]1[cH:10][cH:11][c:12]([CH:15]2[CH2:16][CH2:17][N:18]([C:21]([O:22][C:23]([CH3:24])([CH3:25])[CH3:26])=[O:27])[CH2:19][CH2:20]2)[cH:13][cH:14]1>>[NH2:8][c:9]1[cH:10][cH:11][c:12]([CH:15]2[CH2:16][CH2:17][NH:18][CH2:19][CH2:20]2)[cH:13][cH:14]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 21940085tert-Butyl 4-(4-aminophenyl)piperidine-1-carboxylate

Product 1

HCID 220478414-(Piperidin-4-yl)aniline

Sources & evidence

ORD record
ord-3ee24bfafc6646e994d474622f0187bc
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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